Vilgelm Laboratory

Translational Oncology Research

RNA interference: Biology and prospects of application in biomedicine and biotechnology


Journal article


A. Vilgelm, S. Chumakov, V. Prassolov
Molecular Biology, 2006

Semantic Scholar DOI PubMed
Cite

Cite

APA   Click to copy
Vilgelm, A., Chumakov, S., & Prassolov, V. (2006). RNA interference: Biology and prospects of application in biomedicine and biotechnology. Molecular Biology.


Chicago/Turabian   Click to copy
Vilgelm, A., S. Chumakov, and V. Prassolov. “RNA Interference: Biology and Prospects of Application in Biomedicine and Biotechnology.” Molecular Biology (2006).


MLA   Click to copy
Vilgelm, A., et al. “RNA Interference: Biology and Prospects of Application in Biomedicine and Biotechnology.” Molecular Biology, 2006.


BibTeX   Click to copy

@article{a2006a,
  title = {RNA interference: Biology and prospects of application in biomedicine and biotechnology},
  year = {2006},
  journal = {Molecular Biology},
  author = {Vilgelm, A. and Chumakov, S. and Prassolov, V.}
}

Abstract

RNA interference is one of the most important mechanisms regulating gene expression. Small interfering RNAs (siRNAs) play an essential role in cell defense against virus infection or retrotransposons. The use of siRNAs gives wide opportunities for treating virus infections and cancer. RNA interference allows rapid construction of monogenic functional knockouts, thereby providing a convenient tool for researchers. The review considers the current views of the mechanisms of RNA interference and modern approaches to its practical application.